Fatigue and Brain Fog Kit

What are the supplements in the kit?

• Adrenal Support - A combination of adaptogenic herbs and nutrients that may help support normal adrenal function.*
• Benfotiamine - A fat-soluble form of thiamine (vitamin B1) that exhibits greater bioavailability than water-soluble forms, and may help to maintain optimal thiamine levels in the body.*
• Carnitine Blend - Combines 400 mg L-carnitine and 100 mg acetyl-L-carnitine, in one convenient capsule. L-carnitine is a derivative of amino acids, and naturally occurs in foods, but significant amounts are only found in dark meats (due to high concentrations of mitochondria). L-carnitine is known for its role in supporting muscle strength, normal fat metabolism, and healthy energy production. Carnitine Blend also contains acetyl-L-carnitine, which has unique brain-supportive properties.*
• Electrolyte Blend - A well-balanced formula that includes the electrolytes sodium, potassium, calcium, magnesium, and chloride, which may contribute to maintaining normal hydration levels. It also includes ingredients such as D-ribose, taurine, vitamin C, quercetin, and citrus bioflavonoids, which play a role in supporting normal electrolyte function, maintaining normal energy production, and aiding in exercise recovery.*
• Magnesium Citrate Powder - Provides 300 mg of magnesium in each one teaspoon serving - a convenient delivery system in a great-tasting lemon flavored powder. It mixes well in water and is very easy to titrate when higher doses are needed. Magnesium Citrate Powder helps promote bowel relaxation when fiber alone is not enough, and supports the ability to fall asleep.*
• Selenium + Myo-Inositol - Contains 83 mcg of selenium, a critical nutrient in regulating thyroid function, as well as 600 mg myo-inositol, a nutrient that serves key functions relating to hormone signal transduction in the endocrine system. Clinical research indicates that this nutrient combination can help support optimal thyroid function.*(2)
• S. Boulardii - Saccharomyces boulardii is a non-pathogenic yeast that acts as a probiotic, supporting optimal gut health and immune function.* This formula contains 10 billion CFU of S. boulardii per serving, does not require refrigeration, and is able to survive the harsh environment of the GI tract to deliver its benefits in the large intestine.
• Thyroid Conversion Support - A specialized blend of nutrients and herbs designed to promote healthy biosynthesis of thyroid hormone including the conversion of thyroxine (T4) to triiodothyronine (T3).*

What are the benefits of the supplements in the Kit?

• Adrenal Support - May help maintain normal cortisol levels, promote healthy function of the hypothalamic-pituitary-adrenal (HPA) axis, and support normal neurotransmitter and hormone production.*
• Benfotiamine - May help to maintain optimal thiamine levels in the body, support the body’s natural process of converting carbohydrates into energy, promote healthy digestion of proteins and fats, and support the proper release of hydrochloric acid. By supporting cellular energy production, Benfotiamine may also help combat occasional fatigue associated with a sluggish metabolism.*
• Carnitine Blend - Provides support for people on vegetarian diets, or when dark meats are consumed in small amounts. It also supports exercise performance through encouraging the body to burn fat during exercise, supports normal energy levels by assisting in the transport of fats as a fuel source, and contributes to healthy weight management by supporting the body's ability to build muscle and burn fat.*
• Electrolyte Blend - May be beneficial for replenishing electrolytes lost after occasional diarrhea, vomiting, or sweating, replenishing electrolytes lost during intense exercise, supporting healthy energy levels, maintaining healthy blood pressure already within the normal range, maintaining normal fluid balance in tissues, and support during periods of occasional stress.*
• Magnesium Citrate Powder - Helps to support healthy magnesium levels, promotes regularity and bowel relaxation, maintains energy levels and metabolic efficiency, balances calcium and reduces the risk for build up in the body, and promotes relaxation and restful sleep.*
• Selenium + Myo-Inositol - Formulated to support healthy thyroid function, healthy hormone balance, a balanced metabolism, and optimal immune function. It contains a blend of selenomethionine and myo-inositol in a range that has been studied for synergistic benefits.*
• S. Boulardii - May be beneficial for supporting a healthy microbial balance, healthy gut lining, and normal secretory immunoglobulin A (SIgA), as well as providing support against pathogens that can damage the gut lining, supporting healthy and regular bowel movements, and balancing levels of opportunistic yeast and bacteria.*
• Thyroid Conversion Support - May help to promote healthy biosynthesis of thyroid hormone, support the normal conversion of T4 to T3, promote energy, mental clarity, and metabolic balance, and support healthy hair growth and thickness.*

How long can I take the supplements in the Kit?
It is ideal to continue energy and mental clarity support for three months to two years, depending on individual level of helpfulness and needs.

Can the supplements be taken with thyroid medication?
Adrenal Support, Benfotiamine, Carnitine, S. Boulardii, Selenium + Myo-inositol, and Thyroid Conversion Support should be taken at least 30 to 60 minutes away from thyroid medications. Magnesium Citrate Powder should be taken at least four hours away from thyroid medications.

Spacing Electrolyte Blend 1 hour away from thyroid medication is generally recommended. However, those that believe the blend may be interfering with their thyroid medication absorption should separate the Electrolyte Blend 4 hours from their thyroid medication.

As with any supplement or lifestyle change, testing your thyroid hormone levels every 30-90 days to see if a medication adjustment is needed, is recommended.

Are there any side effects I should be aware of when taking the supplements in this kit?
Carnitine does have a "moving" mechanism, so taking too much may cause loose stools. Other possible side effects of L-Carnitine can include agitation, dry mouth, headache, insomnia, reduced appetite, and may cause a fish-like body odor.

What if I am sensitive to one of the supplement ingredients in the Kit?
If you are sensitive to one of the supplement ingredients, but still want to utilize one or more other supplements in the Kit, you can order them individually:

Adrenal Support

Benfotiamine

Carnitine Blend

Electrolyte Blend

Magnesium Citrate Powder

Selenium + Myo-Inositol

S. Boulardii

Thyroid Conversion Support

Please Note: The Warnings and Precautions below include those for all supplements within the Fatigue and Brain Fog Kit. For information in regards to a specific product within the Kit, please refer to the individual product page.

Not to be used by those with a corn allergy, high blood pressure, an indwelling vascular catheter, those who are immunocompromised, those with risk factors for adverse events (e.g. patients with central venous catheters or increased bacterial translocation), those who have kidney disease or who may be already taking supplements such as cleavers (a diuretic herb) that can affect the kidneys or the lymphatic system, those with peripheral vascular disease, liver disease due to alcoholism (cirrhosis), diabetes, or a history of seizures.

Do not use if you are sensitive to nightshades and/or licorice, or if you are allergic or sensitive to any of the ingredients in this Kit. Adrenal Support and Thyroid Conversion Support contain ashwagandha, which can be reactive for some people with nightshade sensitivities. Adrenal Support contains licorice root, which may exacerbate water retention and high blood pressure.

Rarely, myo-inositol has been associated with nausea, headaches, dizziness, fatigue or sleeplessness. Some people have reported increased bleeding with the use of myo-inositol, so it is not recommended with a history of heavy bleeding, or in those taking blood thinners. If you experience any of these effects, discontinue taking it.

People with diabetes taking any form of myo-inositol should watch for signs of low blood sugar (hypoglycemia), as myo-inositol may lower blood sugar and hemoglobin A1c levels. Selenium intake may also cause side effects in those with diabetes.

Those with a CBS gene mutation have difficulty breaking down selenium. If you know you have a CBS gene mutation, then regularly monitoring your selenium levels is necessary. 

Selenium supplements are also associated with a risk of non-melanoma skin cancer (squamous cell carcinoma), so people at high risk of skin cancer should not take these supplements. In addition, there is possibly a link between selenium and prostate cancer, although data on this topic is conflicting.

Consult with a doctor before use if pregnant or breastfeeding, if you have a history of heavy bleeding, or if a yeast allergy or Crohn’s disease is present.⁺

DO NOT TAKE if taking the following medications: ACE inhibitors, acenocoumarol, alkylating agents, aluminum, aminoglycoside angiotensin receptor blockers, amiodarone, antibiotics, anticoagulant/antiplatelet drugs, antidiabetic drugs, antihypertensive drugs, antitumor antibiotics, antacids, antithyroid drugs, atorvastatin, aspirin, AZT, barbiturates, blood thinners (including warfarin), benzodiazepines, bisphosphonates, calcium channel blockers, calcipotriene, cephalexin, cisplatin, choline magnesium trisalicylate, CNS depressants, contraceptive drugs, corticosteroids, cytochrome P450 1A2, 2B6 2C8, 2C9, 2C19, 3A4 (CYP3A4) substrates, cyclosporine, digoxin, doxorubicin, diuretics, didanosine, diltiazem, escitalopram, estrogens, ethacrynic acid, fluphenazine, furosemide, hepatotoxic drugs, HMG-CoA reductase inhibitors, immunosuppressants, indinavir, insulin, integrase inhibitors, isotretinoin (Accutane), ketamine, levodopa/carbidopa, lithium, losartan, midazolam, monoamine oxidase inhibitors, niacin, organic anion-transporting polypeptide substrates, paclitaxel, penicillamine, pentobarbital, P-glycoprotein substrates, phenobarbital, phenytoin, potassium-sparing diuretics, propranolol, quinolone antibiotics, retinoids, ritonavir, rosuvastatin, salsalate, selumetinib, skeletal muscle relaxers, sulfonylureas, sodium phosphates, sulfonylureas, tamoxifen, tetracycline antibiotics, thiazide diuretics, thyroid hormone⁺⁺, tolvaptan, and/or verapamil.

Selenium may also interact with other supplements and medications, such as cholesterol-lowering statin drugs, antacids, chemotherapy drugs, corticosteroids, and niacin.

Adrenal Support may also interact with alcohol.

Carnitine may also affect Hormone Replacement Therapy, and may increase or cause an imbalance in testosterone levels.

In rare cases, S. Boulardii may cause skin rashes or itchiness. If you experience these effects, discontinue taking it and consult with your practitioner.

Thiamine supplementation should be avoided by those with advanced cancers. As thiamine is necessary for cell replication, tumors may steal the body’s reserves of thiamine and use it to proliferate. Those with thiamine deficiency and cancer may benefit from working with an integrative cancer specialist, as some studies have found an inverse dose-response to thiamine in those with advanced tumors, where the effect changes as the dose increases.

⁺In some cases of Crohn’s disease, S. boulardii may cross-react with antibodies to anti-Saccharomyces cerevisiae (another type of yeast). There is also potential for cross-reactions with yeast allergies. These cases are rare, but should be discussed with your provider before starting S. boulardii, to make sure it is appropriate for your needs.

⁺⁺Note regarding thyroid hormone: This product is not recommended for those with hyperthyroidism, as ashwagandha has been found to increase thyroid hormones. In addition, myo-inositol supplementation has been shown to reduce thyroid antibodies, reduce TSH levels, and even achieve remission in people with Hashimoto’s. As recommended with any lifestyle interventions, individuals with hypothyroidism and normal thyroid function should monitor their levels of thyroid hormones while taking this supplement, and test thyroid hormone levels every 30-90 days to see if a medication adjustment is needed.

Please note: Adrenal Support, Electrolyte Blend, Magnesium Citrate Powder, Selenium + Myo-Inositol, and Thyroid Conversion Support use non-GMO corn-derived ingredients and may contain a protein component that could cause an allergic response in those with corn allergies.

References for information related to the supplements in this Kit can be viewed through the links below:

Adrenal Support

Benfotiamine

Carnitine Blend

Electrolyte Blend

Magnesium Citrate Powder

Selenium + Myo-Inositol

S. Boulardii

Thyroid Conversion Support