HP Restore

What is HP Restore? 
HP Restore is a blend of botanical extracts which helps support the microbes in the gut and maintain a healthy gastric mucosa.* It contains vitamin C, zinc, mastic gum, methylmethionine sulfonium chloride (Vitamin U), and deglycyrrhizinated licorice extract. 

What are the benefits of HP Restore? 
HP Restore helps to rebalance organisms in the stomach and restore a healthy intestinal lining. It may be helpful in managing occasional heartburn, bloating, abdominal pain, or upset stomach.* It is offered in a quick-release capsule, which dissolves easily for fast action.

What is the recommended dose? 
Two capsules, twice per day is recommended.

When should I take it? 
Between meals, on an empty stomach (at least 90 minutes after eating and 45 minutes before eating).

Can it be taken with thyroid medications? 
HP Restore should be taken at least 30 to 60 minutes away from thyroid medications. Mastic gum may help with reducing H. pylori-induced malabsorption of thyroid hormones, and may result in lowered requirements of thyroid hormones. (2, 3, 4) Testing your thyroid hormone levels every 30-90 days to see if a medication adjustment is needed, is recommended. 

How long can I take HP Restore for? 
This supplement can be taken for one to two months.

Are there any side effects that I should be aware of when taking HP Restore? 
May cause headaches, nausea, vomiting, constipation, diarrhea, esophagitis, heartburn, abdominal cramps, and/or gastrointestinal obstruction. May also cause fatigue, headache, insomnia, and/or sleepiness.

Do not take if you have high blood pressure, or are allergic to mastic trees.

Consult with a physician before use if pregnant or breastfeeding.

DO NOT TAKE if taking the following medications: alkylating agents, aluminum, antihypertensive drugs, antitumor antibiotics, blood thinners, cisplatin, corticosteroids, cytochrome P450 2B6, 2C19, 2C8, 2C9, 3A4 substrates; digoxin, diuretic drugs, estrogens, fluphenazine, indinavir, levothyroxine*, loop diuretics, midazolam, P-glycoprotein substrates, and/or paclitaxel

*Note: Precautions with Thyroid Hormone: Mastic gum may help with reducing H. pylori induced malabsorption of thyroid hormones, and may result in lowered requirements of thyroid hormones.(6, 7, 8) Testing thyroid hormone levels every 30-90 days to see if a medication adjustment is needed, is recommended while supplementing with HP Restore.

1. Natural Medicines Therapeutic Research Collaboration. https://naturalmedicines.therapeuticresearch.com/. Accessed March 1, 2022.
2. Dabos KJ, Sfika E, Vlatta LJ, Giannikopoulos G. The effect of mastic gum on Helicobacter pylori: a randomized pilot study. Phytomedicine. 2010;17(3-4):296-299. doi:10.1016/j.phymed.2009.09.010
3. Caron P, Grunenwald S, Persani L, Borson-Chazot F, Leroy R, Duntas L. Factors influencing the levothyroxine dose in the hormone replacement therapy of primary hypothyroidism in adults [published online ahead of print, 2021 Oct 20]. Rev Endocr Metab Disord. 2021;1-21. doi:10.1007/s11154-021-09691-9
4. Castellana M, Castellana C, Giovanella L, Trimboli P. Prevalence of gastrointestinal disorders having an impact on tablet levothyroxine absorption: should this formulation still be considered as the first-line therapy?. Endocrine. 2020;67(2):281-290. doi:10.1007/s12020-019-02185-4