ProB 50

What is ProB 50? 
ProB 50 is a highly potent, shelf-stable, gluten- and dairy-free probiotic formulation containing 50 billion colony-forming units (CFUs) per serving. This formula is delivered in gastro-resistant capsules and consists of 18 well-researched, identity-certified HOWARU^® probiotic strains, selected for their complementary actions, safety, viability, and stability. The use of nitrogen-purged blister packaging further enhances the preservation of these strains, removing the need for refrigeration.

What are the benefits of ProB 50? 
ProB 50 may be beneficial for supporting optimal digestion and nutrient assimilation, maintaining a healthy balance of bacteria in the gut, supporting a normal immune response, and maintaining bowel regularity. It can also help replenish beneficial bacteria in the gut, such as after a course of antibiotics. The capsules are gastro-resistant, come in nitrogen-purged blister packaging, and do not require refrigeration, making ProB 50 a practical option for those with a busy lifestyle.*

What is the recommended dose? 
The recommended dose is one capsule per day.

When should I take it? 
This supplement should be taken with water.

Can it be taken with thyroid medications? 
ProB 50 should be taken at least 30 to 60 minutes away from thyroid medications. Testing your thyroid hormone levels every 30-90 days to see if a medication adjustment is needed, is recommended.

How long can I take ProB 50 for? 
ProB 50 can be taken for one month or long-term.

Are there any side effects that I should be aware of when taking ProB 50? 
ProB 50 may cause gastrointestinal side effects such as epigastric discomfort, abdominal pain, dyspepsia, rumbling, bloating, diarrhea, flatulence, and/or burping.

Consult with a physician before use if pregnant or breastfeeding.

DO NOT TAKE if taking the following medications: antibiotics+ and/or blood thinners.

+ProB50 is a formulation of lactobacillus and bifidobacterium probiotics. The recommendation to avoid taking probiotics while taking antibiotics is based on the fact that antibiotics could reduce the effectiveness of probiotics. However, research shows that taking probiotics while taking antibiotics can help prevent diarrhea which may result from the use of antibiotics. To prevent destruction of probiotic activity, it is recommended to take probiotics and antibiotics at least two hours apart from one another. (2, 3)

1. Natural Medicines Therapeutic Research Collaboration. https://naturalmedicines.therapeuticresearch.com/. Accessed March 1, 2022.
2. Hempel S, Newberry SJ, Maher AR, et al. Probiotics for the prevention and treatment of antibiotic-associated diarrhea: a systematic review and meta-analysis. JAMA. 2012;307(18):1959-1969. doi:10.1001/jama.2012.3507
3. Probiotics for digestive health. Pharmacist’s Letter. 2006;7(22):220704.